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Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.
Gene Name: | chloride channel, voltage-sensitive 5 |
Family/Subfamily: | Ion Channel , Chloride channel - CLC |
Synonyms: | CLCN5, DENTS, CLC5, HCIC-K2, Nephrolithiasis 1 (X-linked), Nephrolithiasis 2, X-linked, NPHL1, NPHL2, XLRH, XRN, Chloride channel 5, Chloride channel protein 5, Chloride transporter ClC-5, ClC-5, CLCK2, HClC-K2 |
Target Sequences: | NM_000084 NP_000075.1 P51795 |
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