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Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Gene Name: | cytosolic iron-sulfur assembly component 1 |
Synonyms: | CIAO1, CIA1, WDR39, WD repeat domain 39, WD40 protein Ciao1 |
Target Sequences: | NM_004804 NP_004795.1 O76071 |
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