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Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.
Gene Name: | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 |
Synonyms: | CHST6, C-GlcNAc6ST, Gn6st-5, HCGn6ST, GlcNAc6ST-5, GST4-beta, MCDC1 |
Target Sequences: | NM_021615 NP_067628.1 Q9GZX3 |
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