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CHST5

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates. However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for SELL. Its substrate specificity may be influenced by its subcellular location.

Gene Name: carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
Synonyms: CHST5, GlcNAc6ST-3, GST4-alpha, Gn6st-3, HIGn6ST, I-GlcNAc-6-ST, I-GlcNAc6ST
Target Sequences: NM_024533 NP_078809.2 Q9GZS9

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).