CHRNE

cholinergic receptor, nicotinic, epsilon (muscle)

CHRNE encodes the epsilon subunit of the nicotinic acetylcholine receptor (nAChR). The nAChR is an ion-conducting channel of the plasma membrane that transmits signal from motor neuron to skeletal muscle in response to binding acetylcholine. It is composed of four subunits in a stoichiometry of alpha 2, beta 1, delta 1, and gamma or epsilon 1. The epsilon subunit is a component of mature nAChRs, as it replaces the embryonic gamma subunit at neuromuscular junctions in newborns. CHRNE null mice display muscle weakness, defects in motor behavior, and premature death. Mutations in the CHRNE gene are responsible for slow-channel congenital myasthenic syndrome (SCCMS).

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Proteins (2)

Type

Recombinant (2)

Target

CHRNE (2)

Publications

No (2)

Tag

GST, N-terminus (1)

His-T7, N-terminus (1)

Species

Human (1)

Mouse (1)

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E. coli (1)

Wheat Germ Extract (1)

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Human CHRNE Protein (Recombinant GST, N-terminus) (aa21-130) - LS-G58137

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse CHRNE Protein (Recombinant His-T7, N-terminus) (Lys21-Lys239) - LS-G133457

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

28.9kDa

Price:

10 µg/$275; 50 µg/$402; 200 µg/$805; 100 µg/$645; 1 mg/$1,881; 500 µg/$1,435; 5 mg/$2,844; 2 mg/$2,065

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