Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
|Gene Name:||cholinergic receptor, nicotinic, beta 1 (muscle)|
|Family/Subfamily:||Ion Channel , Nicotinic acetylcholine receptor|
|Synonyms:||CHRNB1, AChR-beta1, ACHRB, CHRNB, CMS1D, Acrb1, SCCMS, CMS2A, NAChR beta1|
|Target Sequences:||NM_000747 NP_000738.2 P11230|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.