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CHRNA9

cholinergic receptor, nicotinic, alpha 9 (neuronal)

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.

Gene Name: cholinergic receptor, nicotinic, alpha 9 (neuronal)
Family/Subfamily: Ion Channel , Nicotinic acetylcholine receptor
Synonyms: CHRNA9, AChR-alpha9, NACHR alpha 9, NACHRA9, HSA243342, NACHR alpha-9
Target Sequences: NM_017581 NP_060051.2 Q9UGM1

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Products
Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
CHRNA9 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
CHRNA9 Protein - 12.5% SDS-PAGE of human CHRNA9 stained with Coomassie Blue
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Wheat Germ Extract
GST
79.64 kDa
2 µg/$439
CHRNA9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
54.78 kDa
100 µg/$710
CHRNA9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
54.78 kDa
20 µg/$215
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).