CHP2

calcineurin-like EF-hand protein 2

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

CHP2 (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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CHP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110453

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.3 kDa

Price:

100 µg/$494

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Human CHP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84339

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.3 kDa

Price:

20 µg/$150

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