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CHD3

chromodomain helicase DNA binding protein 3

CHD3 is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Gene Name: chromodomain helicase DNA binding protein 3
Synonyms: CHD3, ATP-dependent helicase CHD3, CHD-3, HZFH, Mi-2a, Mi2-ALPHA, ZFH, Zinc finger helicase
Target Sequences: U91543 AAC39923.1 Q12873

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CHD3 (5)
No (5)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
CHD3 Protein
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E. coli
His, N-Terminal
25.7 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
CHD3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
226.4 kDa
100 µg/$710
CHD3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CHD3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
226.4 kDa
20 µg/$215
CHD3 Protein - Recombinant Chromodomain Helicase DNA Binding Protein 3 By SDS-PAGE
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E. coli
His-T7
27.5 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).