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CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Gene Name: complement factor B
Family/Subfamily: Protease , Serine S1
Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
Target Sequences: NM_001710 NP_001701.2 P00751

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Products
ELISA Kits (26)
Competitive EIA (1)
Custom (3)
Sandwich (22)
CFB / Complement Factor B (26)
Human (8)
Mouse (6)
Rat (5)
Chicken (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Rhesus monkey (1)
96-Well Microplate (3)
96-Well Strip Plate (23)
No (26)
Cell Supernatant (1)
Plasma (21)
Serum (21)
Tissue Homogenates (4)
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$893
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$834
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Microplate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CFB / Complement Factor B ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
25 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$1,023
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
100 - 2500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
10 - 250 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
CFB / Complement Factor B ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
CFB / Complement Factor B ELISA Kit
Select
Custom
96-Well Strip Plate
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$783
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CFB / Complement Factor B ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$672
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$1,081
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$1,041
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,100
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Microplate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Viewing 1-25 of 26 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).