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CETN1 encodes centrin 1, which plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. Centrin 1 contains 4 putative EF-hand calcium-binding domains, is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
Gene Name: | centrin, EF-hand protein, 1 |
Synonyms: | CETN1, Caltractin isoform 2, Centrin-1, Caltractin, CETN, Calcium binding protein, CEN1, Centrin, EF-hand protein, 1, EF-hand protein |
Target Sequences: | NM_004066 NP_004057.1 Q12798 |
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