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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CEP290

centrosomal protein 290kDa

CEP290 is a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

Gene Name: centrosomal protein 290kDa
Synonyms: CEP290, 3H11Ag, Cancer/testis antigen 87, Centrosomal protein of 290 kDa, CTCL tumor antigen se2-2, CT87, Centrosomal protein 290kDa, JBTS5, JBTS6, Meckel syndrome, type 4, Nephrocytsin-6, NPHP6, POC3, KIAA0373, Rd16, MKS4, SLSN6, BBS14, Nephrocystin-6, Prostate cancer antigen T21, Tumor antigen se2-2
Target Sequences: NM_025114 NP_079390.3 O15078

Filtered By: None
Target
CEP290 (13)
Reactivity
Human (13)
Mouse (4)
Rat (1)
Bovine (1)
Horse (2)
Monkey (1)
Application
IHC (3)
IHC-P (2)
WB (6)
ELISA (6)
ICC (2)
IF (3)
IP (1)
Peptide-ELISA (3)
Host
rabbit (11)
goat (2)
Isotype
IgG (8)
Clonality
polyclonal pc (13)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (10)
Epitope
aa2429-2479 (2)
740-820 aa, Internal (1)
C-Terminus (1)
Internal (1)
Phe812 (1)
aa1428-1440 (1)
aa521-535 (1)
aa771-820 (1)
Publications
No (13)
Showing 1-13 of 13 results

CEP290 Antibody (aa771-820) IHC-plus™ LS-B9714
Rabbit Polyclonal (IgG) to Human CEP290
Mouse, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-CEP290 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from K562 cells, using CEP290 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-CEP290 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from K562 cells, using CEP290 Antibody. The lane on the right is blocked with the synthesized peptide.

CEP290 Antibody (C-Terminus) LS-C153392
Rabbit Polyclonal to Mouse CEP290
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
100µg 100µl 1mg/ml  $345.00

CEP290 Antibody LS-C677506
Rabbit Polyclonal (IgG) to Human CEP290
Human
ELISA IF IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100

CEP290 Antibody (HRP) LS-C677509
Rabbit Polyclonal (IgG) to Human CEP290
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

CEP290 Antibody (Biotin) LS-C677507
Rabbit Polyclonal (IgG) to Human CEP290
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

CEP290 Antibody (FITC) LS-C677508
Rabbit Polyclonal (IgG) to Human CEP290
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

CEP290 Antibody (aa2429-2479) LS-C288447
Rabbit Polyclonal (IgG) to Human CEP290
Horse, Human
ICC IF IP WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human CEP290 by Immunocytochemistry. Sample: NBF-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-CEP290 used at a dilution of 1:500. Detection: Red-fluorescent goat anti-rabbit IgG cross-adsorbed Antibody DyLight 594 (A120-601D4) used at a dilution of 1:100.
Detection of Human CEP290 by Immunocytochemistry. Sample: NBF-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-CEP290 used at a dilution of 1:500. Detection: Red-fluorescent goat anti-rabbit IgG cross-adsorbed Antibody DyLight 594 (A120-601D4) used at a dilution of 1:100.

CEP290 Antibody (aa2429-2479) LS-C286600
Rabbit Polyclonal (IgG) to Human CEP290
Horse, Human
ICC IF
Unconjugated
100µl  $415.00
Detection of Human CEP290 by Immunocytochemistry. Sample: NBF-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-CEP290 (-2) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG cross-adsorbed Antibody DyLight 594 (A120-601D4) used at a dilution of 1:100.
Detection of Human CEP290 by Immunocytochemistry. Sample: NBF-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-CEP290 (-2) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG cross-adsorbed Antibody DyLight 594 (A120-601D4) used at a dilution of 1:100.

CEP290 Antibody (740-820 aa, Internal) LS-C382649
Rabbit Polyclonal (IgG) to Human CEP290
Mouse, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of CEP290 antibody
Western blot of CEP290 antibody

CEP290 Antibody (Internal) LS-C353558
Rabbit Polyclonal to Human CEP290
Bovine, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of CEP290 expression in HeLa (A); CCRFCEM (B) whole cell lysates.
Western blot analysis of CEP290 expression in HeLa (A); CCRFCEM (B) whole cell lysates.

CEP290 Antibody (Phe812) LS-C177808
Rabbit Polyclonal to Human CEP290
Mouse, Human
WB
Unconjugated
100µl  $345.00
Western blot of CEP290 (F812) pAb in extracts from K562 cells.
Western blot of CEP290 (F812) pAb in extracts from K562 cells.

CEP290 Antibody (aa1428-1440) LS-C61718
Goat Polyclonal to Human CEP290
Human, Monkey
Peptide-ELISA
Unconjugated
100µg  $335.00

CEP290 Antibody (aa521-535) LS-C108890
Goat Polyclonal to Human CEP290
Human
Peptide-ELISA
Unconjugated
100µg  $405.00
Showing 1-13 of 13 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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