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GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.
Gene Name: | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | AGAP1, AGAP-1, Centaurin, gamma 2, CENTG2, Cnt-g2, KIAA1099, GGAP1, Centaurin-gamma-2 |
Target Sequences: | NM_014914 NP_055729.2 Q9UPQ3 |
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