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Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore.
Gene Name: | centromere protein K |
Synonyms: | CENPK, Centromere protein K, CEMPK, AF5alpha, ICEN37, p33, Protein AF-5alpha, Leucine zipper protein FKSG14, Solt, CENP-K, FKSG14 |
Target Sequences: | NM_022145 NP_071428.2 Q9BS16 |
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