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CENPK

centromere protein K

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore.

Gene Name: centromere protein K
Synonyms: CENPK, Centromere protein K, CEMPK, AF5alpha, ICEN37, p33, Protein AF-5alpha, Leucine zipper protein FKSG14, Solt, CENP-K, FKSG14
Target Sequences: NM_022145 NP_071428.2 Q9BS16

Publications (1)

1
Overexpression of centromere protein K (CENP-K) gene in hepatocellular carcinoma promote cell proliferation by activating AKT/TP53 signal pathway. Wang H, Liu W, Liu L, Wu C, Wu W, Zheng J, Zhang M, Chen X, Zhou B, Gao Z, Huang J. Oncotarget. 2017 8:73994-74005. (WB; Human) [Full Text Article] [PubMed:29088763] [PMC:PMC5650318] Related Antibodies: LS-B9423.

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CENPK ELISA Kit
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23.5 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).