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CELA2B / ELA2B
chymotrypsin-like elastase family, member 2B
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.
| Gene Name: | chymotrypsin-like elastase family, member 2B |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | CELA2B, Elastase IIB, Elastase-2B, ELA2B, Pancreatic elastase IIB, Peiib, Elastase 2B, RP11-265F14.2 |
| Target Sequences: | NM_015849 NP_056933.2 P08218 |
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