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Cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene.
Gene Name: | chromatin licensing and DNA replication factor 1 |
Synonyms: | CDT1, Double parked homolog, DUP, RIS2, DNA replication factor Cdt1 |
Target Sequences: | Q9H211 Q9H211 |
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