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CDKL2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

CDKL2 belongs to the CDKL subfamily. CDKL2 has been suggested to be important in learning and memory. Multiple variants of CDKL2 are generated by alternative splicing and intraexonal termination, resulting in diverse carboxy-terminal regulatory domains. Two alternative promoters linked to distinct noncoding exons direct the expression of KKIAMRE.

Gene Name: cyclin-dependent kinase-like 2 (CDC2-related kinase)
Family/Subfamily: Protein Kinase , CDKL
Synonyms: CDKL2, CDC2-related kinase, Cyclin-dependent kinase-like 2, Kkm, KKIAMRE, Protein kinase p56 KKIAMRE, p56 KKIAMRE protein kinase, p56
Target Sequences: NM_003948 NP_003939.1 Q92772

Publications (1)

1
Loss of cyclin-dependent kinase-like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion. Fang CL, Uen YH, Chen HK, Hseu YC, Lin CC, Hung ST, Sun DP, Lin KY. Cancer medicine. 2018 0;0: (Human) [Full Text Article] [PubMed:29790675] [PMC:PMC6051174] Related Antibodies: LS-B4479.

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Products
Antibodies (27)
Primary (27)
CDKL2 (27)
Human (27)
Mouse (6)
Rat (5)
Bat (3)
Bovine (3)
Dog (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (4)
Orangutan (3)
Pig (3)
Rabbit (3)
Xenopus (3)
IHC (10)
IHC-P (4)
WB (27)
ELISA (4)
IF (1)
Peptide-ELISA (2)
rabbit (14)
mouse (13)
Product Group
IHCPlus (1)
IgG (5)
IgG1 (8)
IgG1,k (1)
IgG2a (2)
IgG2b (2)
monoclonal mc (13)
polyclonal pc (14)
1F6 (1)
OTI10H3 (2)
OTI12C2 (2)
OTI1D1 (2)
OTI2D8 (2)
OTI4D2 (2)
OTI5D9 (2)
Biotin Conjugated (1)
Carrier-free (6)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (24)
aa291-493 (12)
N-Terminus (4)
180-260 aa, Internal (1)
Internal (1)
Leu240 (1)
aa211-260 (1)
aa226-255 (1)
No (26)
Yes (1)
CDKL2 Antibody - Anti-CDKL2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IHC-plus™ CDKL2 Antibody (clone 1F6) LS-B4479
(5.0) Rating
(1) Publication(s)
CDKL2 Mouse anti-Human Monoclonal (1F6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CDKL2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDKL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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CDKL2 Antibody (aa291-493, clone OTI5D9) LS-C339655
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (OTI5D9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDKL2 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDKL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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CDKL2 Antibody (aa291-493, clone OTI5D9, Carrier-free) LS-C790663
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (Carrier-free) (OTI5D9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CDKL2 Antibody - CDKL2 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDKL2 Antibody (N-Terminus) LS-C112223
CDKL2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CDKL2 Antibody - CDKL2 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDKL2 Antibody (N-Terminus, Biotin) LS-C465263
CDKL2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey, Orangutan
WB
Biotin Conjugated
100 µl/$469
CDKL2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDKL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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CDKL2 Antibody (aa291-493, clone OTI12C2) LS-C339648
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (OTI12C2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDKL2 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CDKL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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CDKL2 Antibody (aa291-493, clone OTI12C2, Carrier-free) LS-C790659
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (Carrier-free) (OTI12C2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CDKL2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CDKL2 Polyclonal Antibody at dilution of 1:25(×200)
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CDKL2 Antibody LS-C831197
CDKL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CDKL2 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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CDKL2 Antibody LS-C804580
CDKL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CDKL2 Antibody (180-260 aa, Internal) LS-C384262
CDKL2 Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CDKL2 Antibody - Immunohistochemical analysis of CDKL2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CDKL2 Antibody (Internal) LS-C354120
CDKL2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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CDKL2 Antibody LS-C659078
CDKL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$386
CDKL2 Antibody - Western blot of KKIAMRE (L240) pAb in extracts from Jurkat cells.
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CDKL2 Antibody (Leu240) LS-C176827
CDKL2 Rabbit anti-Human Polyclonal (Leu240) Antibody
Human
IHC, WB
Unconjugated
100 µl/$391
CDKL2 Antibody - Western blot analysis of extracts from 293 cells and Jurkat cells, using CDKL2 antibody.
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CDKL2 Antibody LS-C823115
CDKL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CDKL2 Antibody - Western blot analysis of lysates from Jurkat and 293 cells, using CDKL2 Antibody. The lane on the right is blocked with the synthesized peptide.
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CDKL2 Antibody (aa211-260) LS-C119184
CDKL2 Rabbit anti-Human Polyclonal (aa211-260) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKL2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI10H3) LS-C339706
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (OTI10H3) Antibody
Human
WB
Unconjugated
100 µl/$434
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CDKL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI10H3, Carrier-free) LS-C798270
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (Carrier-free) (OTI10H3) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKL2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI2D8) LS-C339636
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (OTI2D8) Antibody
Human
WB
Unconjugated
100 µl/$434
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CDKL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI2D8, Carrier-free) LS-C790649
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (Carrier-free) (OTI2D8) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKL2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI1D1) LS-C339629
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (OTI1D1) Antibody
Human
WB
Unconjugated
100 µl/$434
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CDKL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI1D1, Carrier-free) LS-C790642
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (Carrier-free) (OTI1D1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKL2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
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CDKL2 Antibody (aa291-493, clone OTI4D2) LS-C339635
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (OTI4D2) Antibody
Human
WB
Unconjugated
100 µl/$434
CDKL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CDKL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKL2.
Select
CDKL2 Antibody (aa291-493, clone OTI4D2, Carrier-free) LS-C790648
CDKL2 Mouse anti-Human Monoclonal (aa291-493) (Carrier-free) (OTI4D2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Select
CDKL2 Antibody LS-C658912
CDKL2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$386
CDKL2 Antibody - Western blot of CDKL2 Center in 293, Jurkat cell line lysates (35 ug/lane). CDKL2 (arrow) was detected using the purified antibody.
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CDKL2 Antibody (aa226-255) LS-C98314
CDKL2 Rabbit anti-Human Polyclonal (aa226-255) Antibody
Human
WB
Unconjugated
400 µl/$393
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