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CDH4 / R Cadherin

cadherin 4, type 1, R-cadherin (retinal)

CDH4 / R Cadherin is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: cadherin 4, type 1, R-cadherin (retinal)
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH4, CAD4, Cadherin-4, R-CAD, RCAD, Retinal cadherin, Retina cadherin, R Cadherin, R-cadherin
Target Sequences: NM_001794 NP_001785.2 P55283

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CDH4 / R Cadherin (5)
No (5)
GST, N-terminus (1)
His,C-terminus (1)
His-GST (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
CDH4 / R Cadherin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CDH4 / R Cadherin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
100.28 kDa
100 µg/$494
CDH4 / R Cadherin Protein - Recombinant Cadherin, Retinal By SDS-PAGE
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E. coli
His-GST
59.2 kDa
10 µg/$288; 50 µg/$482; 100 µg/$772; 200 µg/$965; 1 mg/$2,098; 500 µg/$1,627; 5 mg/$3,375; 2 mg/$2,288
CDH4 / R Cadherin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
100.28 kDa
20 µg/$150
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HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
80 kDa
100 µg/$721
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).