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CDH17 / Cadherin 17

cadherin 17, LI cadherin (liver-intestine)

CDH17 / Cadherin 17 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Gene Name: cadherin 17, LI cadherin (liver-intestine)
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH17, Cadherin 16, Cadherin-16, HPT1, Human peptide transporter 1, LI cadherin, HPT-1, HPT-1 cadherin, BILL-cadherin, Cadherin, Cadherin-17, LI-cadherin, Liver-intestine cadherin
Target Sequences: NM_004063 NP_004054.3 Q12864

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Products
Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
CDH17 / Cadherin 17 (9)
No (9)
6His, C-terminus (2)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (6)
Rat (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Human Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (3)
CDH17 / Cadherin 17 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
86.4 kDa
100 µg/$721
CDH17 / Cadherin 17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.15 kDa
100 µg/$494
CDH17 / Cadherin 17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.21 kDa
100 µg/$710
CDH17 / Cadherin 17 Protein - Recombinant  Cadherin 17 By SDS-PAGE
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E. coli
His-T7
35.8 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
86kD
10 µg/$316; 50 µg/$519; 500 µg/$1,533; 1 mg/$2,055
CDH17 / Cadherin 17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.15 kDa
20 µg/$150
CDH17 / Cadherin 17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.21 kDa
20 µg/$215
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
86.0 kDa
10 µg/$317; 50 µg/$524
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).