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CDC42EP3 is a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
Gene Name: | CDC42 effector protein (Rho GTPase binding) 3 |
Synonyms: | CDC42EP3, CEP3, BORG2, Cdc42 effector protein 3, Binder of Rho GTPases 2, CRIB-containing BORG2 protein, MSE55-related protein, UB1 |
Target Sequences: | NM_006449 NP_006440.2 Q9UKI2 |
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