CDC27

cell division cycle 27

CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

CDC27 (5)

Publications

No (5)

Tag

His-T7, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

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Purified (1)

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CDC27 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124319

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

92.4 kDa

Price:

100 µg/$710

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Human CDC27 Protein (Recombinant His-T7, N-terminus) (Asn17-Ser231) - LS-G133308

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

27.9kDa

Price:

10 µg/$275; 50 µg/$402; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human CDC27 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78312

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

92.4 kDa

Price:

20 µg/$215

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Human CDC27 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78313

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

91.7 kDa

Price:

20 µg/$215

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CDC27 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99387

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

91.7 kDa

Price:

100 µg/$710

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