CDC25B

cell division cycle 25B

CDC25B, a CDC25 dual specificity protein phosphatase, has been shown to affect cell cycle regulation by activating cyclin-dependent kinases Cdk1 and Cdk2 during G2 phase. CDC25B also has been shown to possess oncogenic properties and has been implicated in lung, breast, esophagus, stomach, ovarian, and other cancers. Recently CDC25B has been shown to be a steroid receptor coactivator and this function is independent of the protein phosphatase activity in vitro. CDC25B deficient mice are viable but the female mice are sterile due to the arrest of cell division in oocytes. At least five mRNA splice variants have been documented for CDC25B.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

CDC25B (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CDC25B Protein (Recombinant His) (aa377-566) - LS-G16315

Source:

E. coli

Tag:

His

Molecular Weight:

23.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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CDC25B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110588

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.6 kDa

Price:

100 µg/$710

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Human CDC25B Protein (Recombinant GST) (Full Length) - LS-G27848

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.92 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CDC25B Protein (Recombinant GST, N-terminus) (aa181-280) - LS-G58062

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CDC25B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77175

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.6 kDa

Price:

20 µg/$215

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Human CDC25B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77176

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.8 kDa

Price:

20 µg/$150

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CDC25B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101767

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.8 kDa

Price:

100 µg/$494

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