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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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CDC25A

cell division cycle 25A

CDC25A, a CDC25 dual specificity protein phosphatase, has been shown to activate the cyclin-dependent kinases at different points of the cell cycle. CDC25A has been shown to affect S phase entry and possibly the initiation of mitosis. CDC25A dephosphorylates cyclin dependent kinases, including Cdk2, Cdk4, as well as non cyclin proteins such as the homeodomain transcription factor cut, the proto-oncogene Raf-1. CDC25A has been implicated in many carcinomas, including those of the colon, lymph node, stomach, ovary, breast. CDC25A is located on chromosome 3p21 in an area frequently involved in karyotypic abnormalities in renal carcinomas, small cell carcinomas of the lung, and benign tumors of the salivary gland.

Gene Name: cell division cycle 25A
Family/Subfamily: Protein Phosphatase , CDC25
Synonyms: CDC25A, CDC25A2-CAG isoform, Cell division cycle 25A, CDC25A phosphatase, CDC25Hu1, M-phase inducer phosphatase 1, CDC25A2
Target Sequences: NM_001789 NP_001780.2 P30304

Publications (1)

1
Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. Chou ST, Yen YC, Lee CM, Chen MS. The Journal of biological chemistry. 2010 285:17833-45. [PubMed:20368335] [PMC:PMC2878547] Related Antibodies: LS-C97430.

Viewing 1-25 of 173 items
CDC25A Antibody - Anti-CDC25A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal to Human CDC25A
Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
CDC25A Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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(1) Publication(s)
Rabbit Polyclonal to Human CDC25A
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
CDC25A Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CDC25A (Phospho-Ser178) Antibody. The picture on the right is blocked with the phospho peptide.
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Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
CDC25A Antibody
Select
Mouse Monoclonal [clone DCS-121] (IgG2a) to Human CDC25A
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100µg   1mg/ml   $335.00
CDC25A Antibody
Select
Mouse Monoclonal [clone DCS-124] (IgG2a) to Human CDC25A
Mouse, Rat, Human
IP, WB
Unconjugated
100µg   1mg/ml   $335.00
CDC25A Antibody
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CDC25A Antibody
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CDC25A Antibody
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CDC25A Antibody
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CDC25A Antibody - Immunohistochemical analysis of CDC25A staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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Rabbit Polyclonal to Human CDC25A
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
CDC25A Antibody
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CDC25A Antibody - Immunohistochemistry of paraffin-embedded human tonsil (germinal center) stained with cdc25A mAb (DCS-121).
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Mouse Monoclonal [clone DCS-121] (IgG2a) to Human CDC25A
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100µg   $345.00
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Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal to Human CDC25A
IF, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IF, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IF, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IF, IHC, WB
HRP Conjugated, Azide-free
200µl   $680.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IF, IHC, WB
PE Conjugated
200µl   $680.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IF, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IF, IHC, WB
AP Conjugated
200µl   $740.00
CDC25A Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CDC25A Rabbit Polyclonal antibody.
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Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IHC, WB
Unconjugated
100µg   0.72mg/ml   $365.00
CDC25A Antibody - Immunohistochemistry of paraffin-embedded human lung carcinoma using CDC25A (Phospho-Ser75) Antibody.
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Rabbit Polyclonal to Human CDC25A
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   $305.00
CDC25A Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using CDC25A Polyclonal Antibody at dilution of 1:50.
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Rabbit Polyclonal (IgG) to Human CDC25A
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl   0.2mg/ml   $205.00; 60µl   0.2mg/ml   $235.00; 120µl   0.2mg/ml   $295.00; 200µl   0.2mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IHC, IP, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CDC25A
Human
ELISA, IHC, IP, WB
FITC Conjugated
200µl   $740.00

Viewing 1-25 of 173 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).