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CDC14B

cell division cycle 14B

Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

Gene Name: cell division cycle 14B
Family/Subfamily: Protein Phosphatase , CDC14
Synonyms: CDC14B, CDC14 homolog B, Cdc14B1, Cdc14B2, Cell division cycle 14b, CDC14B3, HCDC14B
Target Sequences: NM_003671 NP_201588.1 O60729

☰ Filters
Antibodies (18)
Proteins (4)
Over-Expression Lysate (2)
Primary (18)
Recombinant (2)
CDC14B (22)
Human (18)
Mouse (2)
IHC (1)
WB (18)
Flo (1)
ELISA (3)
IF (1)
IP (6)
Peptide-ELISA (1)
rabbit (17)
mouse (1)
IgG (15)
polyclonal pc (18)
APC Conjugated (2)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (8)
aa188-215 (1)
No (22)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
CDC14B Antibody - Western blot of CDC14B Antibody in 293 cell line lysates (35 ug/lane). CDC14B (arrow) was detected using the purified antibody.
Select
CDC14B Rabbit anti-Human Polyclonal (aa188-215) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
CDC14B Antibody - 1:100 staining human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
CDC14B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CDC14B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
CDC14B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
CDC14B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
CDC14B Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
Select
CDC14B Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Select
CDC14B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
IP, WB
HRP Conjugated
100 µl/$982
Select
CDC14B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
IP, WB
Biotin Conjugated
100 µl/$982
Select
CDC14B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
IP, WB
FITC Conjugated
100 µl/$982
Select
CDC14B Rabbit anti-Human Polyclonal (APC) Antibody
Human
IP, WB
APC Conjugated
100 µl/$982
Select
CDC14B Rabbit anti-Human Polyclonal (PE) Antibody
Human
IP, WB
PE Conjugated
100 µl/$982
Select
CDC14B Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
CDC14B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
CDC14B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
CDC14B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
CDC14B Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
CDC14B Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
CDC14B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
52.1 kDa
100 µg/$710
CDC14B Protein - 12.5% SDS-PAGE of human CDC14B stained with Coomassie Blue
Select
Wheat Germ Extract
GST
80.6 kDa
2 µg/$439
CDC14B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CDC14B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
52.1 kDa
20 µg/$215
Viewing 1-22 of 22 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).