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CDA / Cytidine Deaminase

cytidine deaminase

CDA / Cytidine Deaminase is an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Gene Name: cytidine deaminase
Synonyms: CDA, Cytidine aminohydrolase, Cytidine deaminase, Small cytidine deaminase, CDD, Cytosine nucleoside deaminase
Target Sequences: NM_001785 NP_001776.1

Publications (1)

1
The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells. Chen CW, Tsao N, Huang LY, Yen Y, Liu X, Lehman C, Wang YH, Tseng MC, Chen YJ, Ho YC, Chen CF, Chang ZF. Cell reports. 2016 August;16:1287-1299. (Human) [Full Text Article] [PubMed:27452458] Related Antibodies: LS-B1823.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CDA / Cytidine Deaminase (5)
No (5)
GST (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
Biologically active (1)
CDA / Cytidine Deaminase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
16 kDa
100 µg/$494
CDA / Cytidine Deaminase Protein
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E. coli
His
Biologically active
100 µg/$361; 500 µg/$739; 20 µg/$261
CDA / Cytidine Deaminase Protein - Recombinant  Cytidine Deaminase By SDS-PAGE
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E. coli
His-T7
19.9 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CDA / Cytidine Deaminase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16 kDa
20 µg/$150
CDA / Cytidine Deaminase Protein - 12.5% SDS-PAGE of human CDA stained with Coomassie Blue
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Wheat Germ Extract
GST
41.8 kDa
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).