Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
Potentials and capabilities of the Extracellular Vesicle (EV) Array. Jørgensen MM, Bæk R, Varming K. Journal of Extracellular Vesicles. 2015 4:26048. (IHC; Human)
Characterization of a Cell-Culturing System for the Study of Contact-Independent Extracellular Vesicle Communication. Revenfeld ALS, Søndergaard EKL, Stensballe A, Bæk R, Jørgensen MM, Varming K. Journal of circulating biomarkers. 2016 February;5:3. (Human)[Full Text Article]
Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation. Revenfeld ALS, Bæk R, Jørgensen MM, Varming K, Stensballe A. International journal of molecular sciences. 2017 July;18:pii: E1603. (Human)[Full Text Article]
Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. Jorgensen M1, Baek R, Pedersen S, Sondergaard EK, Kristensen SR, Varming K. Journal of Extracellular Vesicles. 2013 Jun 18;2: [Full Text Article]
Related Antibodies: LS-C35419.