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CD82

CD82 molecule

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: CD82 molecule
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: CD82, 4F9, C33, C33 antigen, CD82 molecule, GR15, IA4, Inducible membrane protein R2, KAI1, Kangai 1, R2, R2 leukocyte antigen, SAR2, ST6, Tetraspanin-27, Tspan-27, TSPAN27, CD82 antigen, Leukocyte surface antigen r2, Metastasis suppressor Kangai-1
Target Sequences: NM_002231 NP_002222.1 P27701

Publications (1)

1
CD82 is a marker to isolate ß cell precursors from human iPS cells and plays a role for the maturation of ß cells. Ami Watanabe, Anna Tanaka, Chizuko Koga, Masahito Matsumoto, Yasushi Okazaki, Tatsuya Kin, Atsushi Miyajima. Scientific reports. 2021 May;11:9530. [Full Text Article] [PubMed:33953224] [PMC:PMC8100138] Related Antibodies: LS-B15130, LS-C742189.

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CD82 ELISA Kit
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Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$870
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).