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CD71 / Transferrin Receptor

Transferrin Receptor

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Gene Name: Transferrin Receptor
Family/Subfamily: Protease , Metallopeptidase M28B
Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1
Target Sequences: NM_003234 NP_003225.2 P02786

☰ Filters
Products
Proteins (23)
Native (1)
Over-Expression Lysate (4)
Recombinant (18)
CD71 / Transferrin Receptor (23)
Bind (1)
ELISA (1)
Func (1)
SDS-PAGE (3)
No (23)
6His, N-terminus (1)
GST, N-terminus (2)
His (1)
His, N-Terminal (2)
His,N-terminus (5)
His-GST (1)
His-S (3)
Human IgG1 Fc, N-terminus (1)
Myc-DDK (Flag) (6)
Chicken (1)
Horse (1)
Human (14)
Mouse (3)
Pig (1)
Rat (1)
293T Cells (2)
E. coli (7)
HEK 293 Cells (8)
Mammalian Cells (3)
Wheat Germ Extract (2)
Purified (6)
Low endotoxin level (7)
Biologically active (1)
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human TFRC consists of 932 amino acids and predicts a molecular mass of 103.6 kDa.
50 µg/$364; 500 µg/$1,452
CD71 / Transferrin Receptor Protein - Recombinant Transferrin Receptor By SDS-PAGE
Select
E. coli
His, N-Terminal
21.3 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
CD71 / Transferrin Receptor Protein - Recombinant Transferrin Receptor By SDS-PAGE
Select
E. coli
His, N-Terminal
27.4 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
CD71 / Transferrin Receptor Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
Mammalian Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
77 kDa
10 µg/$266; 50 µg/$335
CD71 / Transferrin Receptor Protein
Select
HEK 293 Cells
His,N-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse TFRC comprises 694 amino acids and predicts a molecular mass of 78.3 kDa. The apparent molecular mass of mouse TFRC is approximately 80 kDa in SDS-PAGE under reducing conditions.
100 µg/$480; 1 mg/$2,324
Select
E. coli
His-S
27.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
CD71 / Transferrin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
84.7 kDa
100 µg/$710
Select
Mammalian Cells
6His, N-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$269; 50 µg/$372; 500 µg/$1,245
Select
HEK 293 Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
77.4 kDa
100 µg/$721; 1 mg/$4,701
Select
Mammalian Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
74.9 kDa
10 µg/$269; 50 µg/$368
CD71 / Transferrin Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD71 / Transferrin Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD71 / Transferrin Receptor Protein - Measured by its binding ability in a functional ELISA. Immobilized human CD71 at 10 µg/ml (100 µl/well) can bind human Transferrin. The EC50 of human Transferrin is 5.6 ng/mL.
Select
HEK 293 Cells
His,N-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human TFRC comprises 689 amino acids and has a predicted molecular mass of 77.4 kDa.
100 µg/$441; 1 mg/$1,991
CD71 / Transferrin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
84.7 kDa
100 µg/$494
CD71 / Transferrin Receptor Protein - Recombinant  Transferrin Receptor By SDS-PAGE
Select
E. coli
His-GST
53.33 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
Select
None
180 kDa, 90 kDa
20 µg/$362
CD71 / Transferrin Receptor Protein - Purified recombinant protein TFRC was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
84.7 kDa
20 µg/$1,107
CD71 / Transferrin Receptor Protein - Purified recombinant protein TFRC was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
84.7 kDa
20 µg/$1,107
CD71 / Transferrin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
84.7 kDa
20 µg/$215
Select
293T Cells
Myc-DDK (Flag)
84.7 kDa
20 µg/$150
CD71 / Transferrin Receptor Protein - Recombinant Transferrin Receptor By SDS-PAGE
Select
E. coli
His-S
27.2 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CD71 / Transferrin Receptor Protein - Recombinant Transferrin Receptor By SDS-PAGE
Select
E. coli
His-S
26.4 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Viewing 1-23 of 23 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).