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CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
| Gene Name: | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| Synonyms: | CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF |
| Target Sequences: | NM_000574 NP_000565.1 P08174 |
Publications (2)
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