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CD39

ectonucleoside triphosphate diphosphohydrolase 1

In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.

Gene Name: ectonucleoside triphosphate diphosphohydrolase 1
Synonyms: ENTPD1, ATPDase, CD39, CD39 antigen, Ecto-apyrase, Ecto-ATPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPase 1, NTPDase-1, NTPDase 1
Target Sequences: NM_001776 NP_001767.3 P49961

Publications (2)

1
The ENTPD1 promoter polymorphism -860 A > G (rs3814159) is associated with increased gene transcription, protein expression, CD39/NTPDase1 enzymatic activity, and thromboembolism risk. Maloney JP, Branchford BR, Brodsky GL, Cosmic MS, Calabrese DW, Aquilante CL, Maloney KW, Gonzalez JR, Zhang W, Moreau KL, Wiggins KL, Smith NL, Broeckel U, Di Paola J. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2017 July;31:2771-2784. [Full Text Article] [PubMed:28302652] [PMC:PMC6137499]
2
Immune related endonucleases and GTPases are not associated with tumor response in patients with advanced non-small cell lung cancer treated with checkpoint inhibitors. H O Ramdani, M Falk, L C Heukamp, S Schatz, M Tiemann, C Wesseler, L Diehl, E Schuuring, H J M Groen, F Griesinger. Pathology, research and practice. 2021 November;227:153651. [Full Text Article] [PubMed:34673351] Related Antibodies: LS-B13080.

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CD39 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD39 Mouse anti-Human Monoclonal (aa38-307) (2B10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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CD39 Mouse anti-Human Monoclonal Antibody
Human
Flo, IP, WB
Unconjugated
100 µg/$558
CD39 Antibody - Flow cytometry of CD39 antibody
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CD39 Mouse anti-Human Monoclonal (BU61) Antibody
Human
Flo, IP, WB
Unconjugated
100 µg/$411
CD39 Antibody - Flow cytometry of CD39 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD39 Mouse anti-Human Monoclonal (FITC) (BU61) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
FITC Conjugated
120 Tests/$446
CD39 Antibody - Flow cytometry of CD39 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD39 Mouse anti-Human Monoclonal (RPE) (BU61) Antibody
Human
Flo, IP, WB
RPE Conjugated
120 Tests/$511
CD39 Antibody - Human peripheral blood lymphocytes stained with purified A1, followed by anti-mouse IgG FITC
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CD39 Mouse anti-Human Monoclonal (A1) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$283
CD39 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD39 Rabbit anti-Human Polyclonal (aa241-486) Antibody
Pig, Human
ICC, IHC-P, WB
Unconjugated
50 µl/$460
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CD39 Rat anti-Mouse Monoclonal (aa38-478) Antibody
Mouse
ELISA, Flo, IP, WB
Unconjugated
100 µg/$941
CD39 Antibody
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CD39 Rabbit anti-Human Polyclonal (aa374-551) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
CD39 Antibody - Western blot of CD39 antibody
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CD39 Rabbit anti-Human Polyclonal (31-80 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CD39 Guinea pig anti-Rat Polyclonal Antibody
Mouse, Rat, Hamster
IHC
Unconjugated
50 µl/$483; 150 µl/$728
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CD39 Mouse anti-Human Monoclonal (6H12F9) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$459
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CD39 Mouse anti-Human Monoclonal (FITC) (A1) Antibody
Human
Flo
FITC Conjugated
0.1 mg/$432
CD39 Antibody - Flow cytometry of CD39 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD39 Mouse anti-Human Monoclonal (Azide-free) (BU61) Antibody
Human
Flo, IP, WB
Unconjugated, Azide-free
100 µg/$411
CD39 Antibody - Western blot analysis of lysates from HeLa and Jurkat cells, using ENTPD1 Antibody. The lane on the right is blocked with the synthesized peptide.
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CD39 Rabbit anti-Human Polyclonal (aa351-400) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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CD39 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
CD39 Antibody - ENTPD1 / CD39 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD39 Rabbit anti-Human Polyclonal (aa112-161) Antibody
Human
WB
Unconjugated
100 µl/$424
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CD39 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$331
CD39 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD39 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
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CD39 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$361
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CD39 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, WB
Biotin Conjugated
100 µg/$626
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CD39 Mouse anti-Human Monoclonal (Low Endotoxin) (A1) Antibody
Human
Flo, IF
Unconjugated, Low Endotoxin
0.5 mg/$671
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CD39 Mouse anti-Human Monoclonal (A1) Antibody
Human
Flo, IF
Unconjugated
0.1 mg/$385
CD39 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ENTPD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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CD39 Mouse anti-Human Monoclonal (aa38-307) (Carrier-free) (2B10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CD39 Antibody - Fig-1: Western blot analysis of hCD39. Anti-hCD39 antibody was used at 2 µg/ml on mouse placenta lysate.
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CD39 Mouse anti-Mouse Monoclonal Antibody
Mouse, Human
Flo, WB
Unconjugated
25 µg/$288; 100 µg/$414
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).