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CD33

CD33 molecule

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Gene Name: CD33 molecule
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: CD33, CD33 antigen, CD33 molecule, gp67, SIGLEC-3, p67, CD33 antigen (gp67), SIGLEC3
Target Sequences: NM_001772 NP_001763.3 P20138

☰ Filters
Products
Proteins (22)
Over-Expression Lysate (8)
Recombinant (14)
CD33 (22)
SDS-PAGE (1)
No (22)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His, C-terminus (2)
Fc (1)
Fc, C-terminus (1)
Fc/6His,C-terminus (1)
Fc-6His, C-terminus (1)
GST (1)
His (1)
His, N-Terminal (1)
His,C-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (10)
Human (14)
Mouse (4)
293T Cells (4)
E. coli (3)
HEK 293 Cells (8)
Human Cells (4)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (7)
Low endotoxin level (8)
CD33 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD33 comprises 253 amino acids and has a predicted molecular mass of 28.2 kDa. The apparent molecular mass of the protein is approximately 40-46 kDa in SDS-PAGE under reducing conditions.
100 µg/$441; 1 mg/$1,991
CD33 Protein - Recombinant Sialic Acid Binding Ig Like Lectin 3 By SDS-PAGE
Select
E. coli
His-T7
28.2 kDa
50 µg/$402; 10 µg/$275; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.29 kDa
100 µg/$494
CD33 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His-SUMO, N-terminus + Myc, C-terminus
46.7 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.3 kDa
100 µg/$494
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.6 kDa
100 µg/$721
Select
Mammalian Cells
Fc/6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
55.0 kDa
10 µg/$269; 50 µg/$368
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.29 kDa
100 µg/$494
CD33 Protein
Select
E. coli
His, N-Terminal
100 µg/$361; 500 µg/$739; 20 µg/$261
CD33 Protein - 12.5% SDS-PAGE of human CD33 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
65.78 kDa
2 µg/$439
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
28.2 kDa
100 µg/$721; 1 mg/$4,701
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
53.1 kDa
100 µg/$721
CD33 Protein - Purified recombinant protein CD33 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
38 kDa
20 µg/$1,107
CD33 Protein - Purified recombinant protein CD33 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$1,107
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.29 kDa
20 µg/$150
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39.73 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
25.29 kDa
20 µg/$150
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.3 kDa
20 µg/$150
CD33 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.73 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7 kDa
10 µg/$288; 50 µg/$436
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
Fc-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
55.01kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-22 of 22 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).