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CD30L / CD153

tumor necrosis factor (ligand) superfamily, member 8

CD30L / CD153 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: tumor necrosis factor (ligand) superfamily, member 8
Family/Subfamily: TNF , not assigned-TNF
Synonyms: TNFSF8, CD153, CD30 antigen ligand, CD30-L, CD30L, CD30LG, CD153 antigen, CD30 ligand
Target Sequences: NM_001244 NP_001235.1 P32971

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
CD30L / CD153 (10)
No (10)
GST (1)
GST, N-terminus (1)
His (2)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
Rat (1)
293T Cells (1)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (2)
Human Cells (1)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (2)
Biologically active (1)
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CHO Cells
His, N-Terminal
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
10 µg/$268; 50 µg/$349
CD30L / CD153 Protein - Purified recombinant protein TNFSF8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
25.8 kDa
20 µg/$1,107
CD30L / CD153 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.8 kDa
100 µg/$494
CD30L / CD153 Protein - 12.5% SDS-PAGE of human TNFSF8 stained with Coomassie Blue
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Wheat Germ Extract
GST
52.4 kDa
10 µg/$479; 25 µg/$670
CD30L / CD153 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
25.8 kDa
20 µg/$150
CD30L / CD153 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
19.6 kDa
200 µg/$928
CD30L / CD153 Protein - Recombinant Cluster Of Differentiation 30 Ligand By SDS-PAGE
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E. coli
His
20.6 kDa
10 µg/$268; 50 µg/$360; 100 µg/$575; 200 µg/$717; 1 mg/$1,748; 500 µg/$1,318; 5 mg/$2,701; 2 mg/$1,927
Select
E. coli
His
20.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CD30L / CD153 Protein - Recombinant Cluster Of Differentiation 30 Ligand By SDS-PAGE
Select
E. coli
His-GST
51.1 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).