CD225 / IFITM1

interferon induced transmembrane protein 1

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

CD225 / IFITM1 (6)

Publications

No (6)

Tag

GST (3)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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CD225 / IFITM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100089

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

13.8 kDa

Price:

100 µg/$494

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Human CD225 / IFITM1 Protein (Recombinant GST) (aa1-36) - LS-G22096

Source:

E. coli

Tag:

GST

Molecular Weight:

31.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CD225 / IFITM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76880

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

13.8 kDa

Price:

20 µg/$150

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Human CD225 / IFITM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66087

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

13.8 kDa

Price:

20 µg/$1,107

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Human CD225 / IFITM1 Protein (Recombinant GST) (Full Length) - LS-G31184

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

39.49 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CD225 / IFITM1 Protein (Recombinant GST) (Full Length) - LS-G31186

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

40.3 kDa

Price:

10 µg/$479; 25 µg/$670

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