CD207 / Langerin

CD207 molecule, langerin

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

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ELISA Kits (1)

Type

Sandwich (1)

Target

CD207 / Langerin (1)

Reactivity

Human (1)

Format

96-Well Microplate (1)

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Sample Type

Cell Culture Supernatants (1)

Plasma (1)

Serum (1)

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Human CD207 / Langerin (Sandwich ELISA) ELISA Kit - LS-F50287

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.102 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$672

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