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CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.
|Gene Name:||CD2 molecule|
|Synonyms:||CD2, CD2 antigen, Erythrocyte receptor, LFA-3 receptor, LFA-2, Lymphocyte-function antigen-2, T11, SRBC, CD2 molecule, Rosette receptor, T-cell surface antigen CD2|
|Target Sequences:||NM_001767 NP_001758.2 P06729|
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