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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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CD1C

CD1c molecule

CD1C is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Gene Name: CD1c molecule
Synonyms: CD1C, BDCA1, CD1, CD1c molecule, CD1C antigen, c polypeptide, CD1c antigen, R7
Target Sequences: NM_001765 NP_001756.2 P29017

Publications (1)

1
Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia. Daridon C, Loddenkemper C, Spieckermann S, Kühl AA, Salama A, Burmester GR, Lipsky PE, Dörner T. Blood. 2012 120:5021-31. (IP; Human) [Full Text Article] [PubMed:22955923]

Viewing 1-25 of 57 items
CD1C Antibody - Anti-CD1C antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Mouse Monoclonal [clone 4C7] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI1H9] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI1H9] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
CD1C Antibody - Flow cytometry of CD1C antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone M241] (IgG1,k) to Human CD1C
Human
Flo, IHC, IHC-Fr
Unconjugated, Azide-free
100µg   1mg/ml   $315.00
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI1F4] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI1F4] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI2D4] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI2D4] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI2B3] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI2B3] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
CD1C Antibody - Flow cytometry of CD1C antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone M241] (IgG1,k) to Human CD1C
Human
Flo, IHC, IHC-Fr
FITC Conjugated
120tst   $345.00
Select
Mouse Monoclonal (IgG1,k) to Human CD1C
Human
Flo
Biotin Conjugated
100µg   $495.00
CD1C Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human CD1C
Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
CD1C Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Goat Polyclonal (IgG) to Human CD1C
Human
ELISA, WB
Unconjugated
100µg   $740.00
CD1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD1C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD1C.
Select
Mouse Monoclonal [clone OTI1E10] (IgG1) to Human CD1C
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100µl   1mg/ml   $345.00
CD1C Antibody - CD1C Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The CD1C antibody detected the CD1C protein (arrow).
Select
Rabbit Polyclonal to Human CD1C
Human
WB
Unconjugated
400µl   $325.00
Select
Mouse Monoclonal [clone 3G1B3] (IgG2b) to Human CD1C
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl   $365.00
Select
Mouse Monoclonal [clone 2A7C11] (IgG2b) to Human CD1C
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl   $365.00
CD1C Antibody - Anti-CD1C antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Mouse Monoclonal [clone 4C7] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
CD1C Antibody - Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100
Select
Rabbit Polyclonal (IgG) to Human CD1C
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $235.00; 100µl   $285.00
Select
Mouse Monoclonal [clone L161] (IgG1) to Human CD1C
Human
Flo, IHC, IP
Unconjugated
0.1mg   1mg/ml   $255.00
CD1C Antibody - Anti-CD1C mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C.
Select
Mouse Monoclonal [clone OTI5A8] (IgG1) to Human CD1C
Human
IF, WB
Unconjugated
100µl   1mg/ml   $345.00
CD1C Antibody - Anti-CD1C mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C.
Select
Mouse Monoclonal [clone OTI5A8] (IgG1) to Human CD1C
Human
IF, WB
Unconjugated, Carrier-free
100µg   $395.00
CD1C Antibody - Immunofluorescent analysis of A549 cells diluted at 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
Rabbit Polyclonal (IgG) to Human CD1C
Human
ELISA, IF, WB
Unconjugated
50µg   $285.00; 100µg   $385.00

Viewing 1-25 of 57 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).