CD163

CD163 molecule

Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

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Products

ELISA Kits (26)

Type

Custom (4)

Sandwich (20)

Sandwich CLIA (2)

Target

CD163 (26)

Reactivity

Human (11)

Mouse (7)

Rat (2)

Dog (1)

Monkey (2)

Pig (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (6)

96-Well Strip Plate (17)

Publications

No (26)

Sample Type

Cell Culture Supernatants (7)

Cell Lysates (2)

Heparin Plasma (1)

Plasma (21)

Serum (22)

Tissue Homogenates (7)

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Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F2855

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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Rat CD163 (Sandwich ELISA) ELISA Kit - LS-F9679

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F9079

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$818

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Monkey CD163 (Sandwich ELISA) ELISA Kit - LS-F32525

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Monkey CD163 (Sandwich ELISA) ELISA Kit - LS-F38523

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F22273

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Pig CD163 (Sandwich ELISA) ELISA Kit - LS-F53501

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

93.75 - 6000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$1,041

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Human CD163 (Sandwich ELISA) ELISA Kit - LS-F13096

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

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Human CD163 (Sandwich ELISA) ELISA Kit - LS-F20668

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse CD163 (Custom ELISA) ELISA Kit - LS-F18375

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$685

Select

Dog CD163 (Custom ELISA) ELISA Kit - LS-F18376

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

Select

Bovine CD163 (Custom ELISA) ELISA Kit - LS-F18377

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Pig CD163 (Custom ELISA) ELISA Kit - LS-F18378

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human CD163 (CLIA) ELISA Kit - LS-F29088

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human CD163 (Sandwich ELISA) ELISA Kit - LS-F24414

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1560 - 100000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

Select

Human CD163 (CLIA) ELISA Kit - LS-F29047

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

40 - 2500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$649

Select

Human CD163 (Sandwich ELISA) ELISA Kit - LS-F2644

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

Select

Human CD163 (Sandwich ELISA) ELISA Kit - LS-F25314

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

Select

Rat CD163 (Sandwich ELISA) ELISA Kit - LS-F22378

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F24745

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

780 - 50000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

Select

Human CD163 (Sandwich ELISA) ELISA Kit - LS-F37246

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CD163 (Sandwich ELISA) ELISA Kit - LS-F57463

Type:

Sandwich

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Sample Types:

Cell Culture Supernatants, Heparin Plasma, Serum

Price:

1 Plate/$795

Select

Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F55854

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F52962

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.9 - 60 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

Select

Human CD163 (Sandwich ELISA) ELISA Kit - LS-F47

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

32.77 - 3200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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