Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CCR5

chemokine (C-C motif) receptor 5 (gene/pseudogene)

CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: chemokine (C-C motif) receptor 5 (gene/pseudogene)
Family/Subfamily: GPCR , Chemokine
Synonyms: CCR5, C-C chemokine receptor 5, CD195 antigen, CD195, C-C CKR-5, Chemokine c-c motif receptor 5, Chemr13, CMKBR5, CKR5, Cc chemokine receptor 5, CCCKR5, CCR-5, Ccr5 receptor, Chemokine receptor CCR5, HIV-1 fusion coreceptor, IDDM22, C-C chemokine receptor type 5, CC-CKR-5, CKR-5
Target Sequences: NM_000579 NP_000570.1 P51681

Publications (4)

1
Identification of a linear peptide recognized by monoclonal antibody 2D7 capable of generating CCR5-specific antibodies with human immunodeficiency virus-neutralizing activity. Khurana S, Kennedy M, King LR, Golding H. Journal of virology. 2005 79:6791-800. (Flo) [PubMed:15890918] [PMC:PMC1112162]
2
Gp120 V3-dependent impairment of R5 HIV-1 infectivity due to virion-incorporated CCR5. Monde K, Maeda Y, Tanaka Y, Harada S, Yusa K. The Journal of biological chemistry. 2007 282:36923-32. [PubMed:17971448]
3
TLR2-dependent pathway of heterologous down-modulation for the CC chemokine receptors 1, 2, and 5 in human blood monocytes. Fox JM, Letellier E, Oliphant CJ, Signoret N. Blood. 2011 117:1851-60. [PubMed:21148810]
4
Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation. O'Boyle G, Fox CR, Walden HR, Willet JD, Mavin ER, Hine DW, Palmer JM, Barker CE, Lamb CA, Ali S, Kirby JA. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:4598-603. [PubMed:22392992] [PMC:PMC3311336]
more

Viewing 1-25 of 116 items
CCR5 Antibody - Anti-CCR5 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Select
Mouse Monoclonal [clone T21/8] (IgG1,k) to Human CCR5
Human
ELISA, Flo, IHC, IHC-P, IP, WB
Unconjugated
50µg   0.5mg/ml   $425.00
Select
Rabbit Polyclonal to Human CCR5
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µg   $590.00
Select
Mouse Monoclonal [clone T21/8] (IgG1) to Human CCR5
Human
ELISA, Flo, ICC, IP, WB
Unconjugated
0.1mg   1mg/ml   $255.00
CCR5 Antibody - Surface staining of CD195 in human peripheral blood with anti-CD195 (T21/8) APC.
Select
Mouse Monoclonal [clone T21/8] (IgG1) to Human CCR5
Human
ELISA, Flo, ICC, IP, WB
APC Conjugated
100tst   $315.00
CCR5 Antibody - Surface staining of CD195 in human peripheral blood with anti-CD195 (T21/8) PE.
Select
Mouse Monoclonal [clone T21/8] (IgG1) to Human CCR5
Human
ELISA, Flo, ICC, IP, WB
PE Conjugated
100tst   $315.00
Select
Goat Polyclonal to Human CCR5
Human, Macaque
ELISA, ICC, IHC, WB
Unconjugated
200µg   $475.00
CCR5 Antibody - IHC-P: CCR5 antibody testing of human rectal cancer tissue
Select
Rabbit Polyclonal (IgG) to Human CCR5
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100µg   $435.00
CCR5 Antibody - Immunohistochemistry of CCR5 in human lymph node tissue with CCR5 antibody at 20 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human CCR5
Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg   $365.00
Select
Rat Monoclonal [clone HEK/1/85a] (IgG2a) to Human CCR5
Human
Flo
FITC Conjugated
0.1mg   $355.00
CCR5 Antibody - Staining of FC-blocked (anti-CD16/32, LS-C107169) BALB/c peritoneal-exudate cells with FITC anti-mouse/human CD11b (M1/70) (LS-C107132) and.5 ug of PE Armenian Hamster IgG isotype control. Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Hamster Monoclonal [clone HM-CCR5 (7A4)] (IgG) to Mouse CCR5
Mouse
Flo
PE Conjugated
50µg   0.2mg/ml   $245.00; 100µg   0.2mg/ml   $275.00; 200µg   $375.00
Select
Mouse Monoclonal [clone 12D1] (IgG2a,k) to Human CCR5
Human
Flo, IF, IHC, IHC-Fr
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
Select
Mouse Monoclonal [clone 12D1] (IgG2a,k) to Human CCR5
Human
Flo, IF, IHC, IHC-Fr
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
CCR5 Antibody - Anti-CCR5 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Goat Polyclonal (IgG) to Human CCR5
Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
50µg   $425.00
CCR5 Antibody - Immunofluorescent analysis of HepG2 cells using CCR5 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
Rabbit Polyclonal (IgG) to Human CCR5
Mouse, Human
ELISA, IF, WB
Unconjugated
50µg   3mg/ml   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human CCR5
Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $530.00
Select
Mouse Polyclonal (IgG) to Human CCR5
Human
Flo, WB
Unconjugated
50µg   $560.00
CCR5 Antibody - Western blot analysis of lysates from COS7 cells, using CCR5 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human CCR5
Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rat Monoclonal [clone 11D98] (IgG) to Mouse CCR5
Mouse
WB
Unconjugated
100µg   $650.00
CCR5 Antibody - CCR5 antibody Western blot. Lane 1: Mouse Lung Tissue Lysate. Lane 2: Mouse Intestine Tissue Lysate. Lane 3: Mouse Kidney Tissue Lysate.
Select
Rabbit Polyclonal to Mouse CCR5
Mouse
WB
Unconjugated
100µg   200µl   0.5mg/ml   $325.00
CCR5 Antibody - Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human CCR5
Mouse, Sheep, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $385.00
CCR5 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human CCR5
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
100µl   1mg/ml   $505.00
Select
Mouse Monoclonal [clone 6G11D1] (IgG1) to Human CCR5
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl   $365.00
Select
Rabbit Polyclonal to Human CCR5
Rat, Human
IP
Magnetic beads Conjugated
100µg   $325.00
CCR5 Antibody - Western blot analysis using CD195 mouse mAb against L-02 (1) cell lysate.
Select
Mouse Monoclonal [clone 6H3D5] (IgG1) to Human CCR5
Human
ELISA, Flo, WB
Unconjugated
100µl   $365.00
Select
Goat Polyclonal (IgG) to Human CCR5
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100µg   $665.00

Viewing 1-25 of 116 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).