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CCP110
centriolar coiled coil protein 110kDa
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
| Gene Name: | centriolar coiled coil protein 110kDa |
| Synonyms: | CCP110, CP110, Centrosomal protein of 110 kDa, KIAA0419, Centrosomal protein CP110, Cep110 |
| Target Sequences: | NM_014711 NP_055526.3 O43303 |
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