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CCNB1 / Cyclin B1

cyclin B1

CCNB1 / Cyclin B1 is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

Gene Name: cyclin B1
Synonyms: CCNB1, CCNB, Cyclin B1, G2/mitotic-specific cyclin-B1, G2/mitotic-specific cyclin B1
Target Sequences: NM_031966 NP_114172.1 P14635

Publications (2)

1
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer. Agarwal R, Gonzalez-Angulo AM, Myhre S, Carey M, Lee JS, Overgaard J, Alsner J, Stemke-Hale K, Lluch A, Neve RM, Kuo WL, Sorlie T, Sahin A, Valero V, Keyomarsi K, Gray JW, Borresen-Dale AL, Mills GB, Hennessy BT. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 15:3654-62. (WB) [PubMed:19470724] [PMC:PMC2887710]
2
The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis. Nascimento EM, Cox CL, MacArthur S, Hussain S, Trotter M, Blanco S, Suraj M, Nichols J, Kbler B, Benitah SA, Hendrich B, Odom DT, Frye M. Nature cell biology. 2011 13:1395-405. (IHC-P; Mouse) [Full Text Article] [PubMed:22101514] [PMC:PMC3242072]

☰ Filters
Products
Proteins (7)
Recombinant (7)
CCNB1 / Cyclin B1 (7)
No (7)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-T7 (1)
Human (7)
Baculovirus (1)
E. coli (3)
Wheat Germ Extract (2)
Yeast (1)
Purified (4)
CCNB1 / Cyclin B1 Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
CCNB1 / Cyclin B1 Protein
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E. coli
His, N-Terminal
48.8 kDa
50 µg/$419
CCNB1 / Cyclin B1 Protein - Recombinant  Cyclin B By SDS-PAGE
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E. coli
His-T7
25.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CCNB1 / Cyclin B1 Protein - 12.5% SDS-PAGE of human CCNB1 stained with Coomassie Blue
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Wheat Germ Extract
GST
74.7 kDa
2 µg/$439
CCNB1 / Cyclin B1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Baculovirus
10His, N-terminus + Myc, C-terminus
100 µg/$1,067; 20 µg/$447; 1 mg/$1,988
CCNB1 / Cyclin B1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CCNB1 / Cyclin B1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).