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CCL3 / MIP-1-Alpha
chemokine (C-C motif) ligand 3
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
| Gene Name: | chemokine (C-C motif) ligand 3 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL3, C-C motif chemokine 3, G0S19-1, Mip1alpha, SCYA3, SIS-beta, Chemokine (C-C motif) ligand 3, LD78ALPHA, MIP-1-alpha, MIP1A, PAT 464.1, Small-inducible cytokine A3 |
| Target Sequences: | NM_002983 NP_002974.1 |
Publications (2)
1
Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study. Xu J, Alexander DB, Iigo M, Hamano H, Takahashi S, Yokoyama T, Kato M, Usami I, Tokuyama T, Tsutsumi M, Tamura M, Oguri T, Niimi A, Hayashi Y, Yokoyama Y, Tonegawa K, Fukamachi K, Futakuchi M, Sakai Y, Suzui M, Kamijima M, Hisanaga N, Omori T, Nakae D, Hirose A, Kanno J, Tsuda H. Cancer science. 2015 106:825-32. (IHC-P; Human)
[Full Text Article]
[PubMed:25940505]
[PMC:PMC4520633]
2
CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Takayuki Kodama, Yu-Ichiro Koma, Noriaki Arai, Aya Kido, Naoki Urakawa, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozaki. Laboratory investigation; a journal of technical methods and pathology. 2020 September;100:1140-1157. [Full Text Article]
[PubMed:32457351]
[PMC:PMC7438203]
Related Antibodies: LS-C384561.
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Products
ELISA Kits
(46)
Type
Custom
(3)
Development Kit
(3)
Sandwich
(36)
Sandwich CLIA
(4)
Target
CCL3 / MIP-1-Alpha
(46)
Reactivity
Human
(13)
Mouse
(12)
Rat
(11)
Chicken
(1)
Dog
(2)
Equine
(1)
Guinea pig
(1)
Monkey
(1)
Porcine
(1)
Rabbit
(1)
Sheep
(1)
Product Group
Coronavirus Detection
(46)
Cytokine Release Syndrome
(46)
DevKit Core
(2)
DevKit DuoPlus
(1)
ELISA Kits for Cytokine Release Syndrome Targets
(46)
Format
1000 Wells
(2)
12 x 8-Well Microstrips
(5)
96-Well Microplate
(11)
96-Well Strip Plate
(26)
Antibody Pair and Standard
(1)
Publications
No
(46)
Sample Type
Cell Culture Supernatants
(17)
Cell Lysates
(10)
Citrate Plasma
(1)
EDTA Plasma
(1)
Heparin Plasma
(1)
Plasma
(34)
Serum
(35)
Tissue Homogenates
(12)
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$488
Sandwich
96-Well Strip Plate
Dog
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Microplate
Human
4.13 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
Sandwich
96-Well Microplate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
12 x 8-Well Microstrips
Rat
16 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$479
Sandwich
96-Well Strip Plate
Porcine
23.438 - 1500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Sheep
11.719 - 750 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
Sandwich
96-Well Strip Plate
Guinea pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Chicken
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Monkey
23.438 - 1500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
Sandwich CLIA
96-Well Strip Plate
Human
11 - 750 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$649
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Development Kit
1000 Wells
Mouse
8 - 500 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
Development Kit
1000 Wells
Rat
16 - 1000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
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