Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
|Gene Name:||chemokine (C-C motif) ligand 25|
|Family/Subfamily:||Intercrine , Intercrine beta|
|Synonyms:||CCL25, C-C motif chemokine 25, Ck beta-15, TECK, Thymus-expressed chemokine, Small-inducible cytokine A25, TECKvar, Chemokine TECK, Ckb15, SCYA25, Thymus expressed chemokine|
|Target Sequences:||NM_005624 NP_005615.2 O15444|
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