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CCL24 / Eotaxin 2

chemokine (C-C motif) ligand 24

CCL24 / Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

Gene Name: chemokine (C-C motif) ligand 24
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL24, C-C motif chemokine 24, Ckb-6, CK-beta-6, Eotaxin2, MPIF-2, MPIF2, SCYA24, Small-inducible cytokine A24, Eotaxin-2
Target Sequences: NM_002991 NP_002982.2 O00175

Publications (2)

1
Eosinophils in Colorectal Neoplasms Associated with Expression of CCL11 and CCL24. Cho H, Lim SJ, Won KY, Bae GE, Kim GY, Min JW, Noh BJ. Journal of pathology and translational medicine. 2016 50:45-51. (IHC, WB; Human) [Full Text Article] [PubMed:26657310] [PMC:PMC4734969]
2
Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue. Trugilho MRO, Hottz ED, Brunoro GVF, Teixeira-Ferreira A, Carvalho PC, Salazar GA, Zimmerman GA, Bozza FA, Bozza PT, Perales J. PLoS pathogens. 2017 May;13:e1006385. [Full Text Article] [PubMed:28542641] [PMC:PMC5453622]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).