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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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CCL16 / LEC
chemokine (C-C motif) ligand 16
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
| Gene Name: | chemokine (C-C motif) ligand 16 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL16, Cc chemokine lcc-1, CKb12, Chemokine hcc-4, Chemokine LEC, Chemokine lmc, ILINCK, Liver CC chemokine-1, Monotactin-1, NCC-4, LCC-1, LEC, Small-inducible cytokine A16, Liver-expressed chemokine, LMC, New CC chemokine 4, C-C motif chemokine 16, Chemokine CC-4, Chemokine ncc-4, HCC-4, IL-10-inducible chemokine, Mtn-1, NCC4, SCYA16, SCYL4 |
| Target Sequences: | NM_004590 NP_004581.1 O15467 |
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