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CCL14

chemokine (C-C motif) ligand 14

Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.

Gene Name: chemokine (C-C motif) ligand 14
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL14, CC-3, C-C motif chemokine 14, Chemokine cc3, Chemokine CC-1/CC-3, Chemokine cc1, Chemokine CC-3, HCC-1(1-74), Hcc3, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, Small-inducible cytokine A14, SY14, CC-1, CKB1, HCC1, Hemofiltrate CC chemokine 1, NCC2, New CC chemokine 2
Target Sequences: NM_004166 NP_004157.1 Q16627

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).