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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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CCL14
chemokine (C-C motif) ligand 14
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
| Gene Name: | chemokine (C-C motif) ligand 14 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL14, CC-3, C-C motif chemokine 14, Chemokine cc3, Chemokine CC-1/CC-3, Chemokine cc1, Chemokine CC-3, HCC-1(1-74), Hcc3, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, Small-inducible cytokine A14, SY14, CC-1, CKB1, HCC1, Hemofiltrate CC chemokine 1, NCC2, New CC chemokine 2 |
| Target Sequences: | NM_004166 NP_004157.1 Q16627 |
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