Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
|Gene Name:||cholecystokinin A receptor|
|Family/Subfamily:||GPCR , Cholecystokinin|
|Synonyms:||CCKAR, CCK-A receptor, CCK-AR, CCKRA, CCK-A, CCKA receptor, Cholecystokinin A receptor, Cck1r, CCK1-R, Cholecystokinin-1 receptor|
|Target Sequences:||NM_000730 NP_000721.1 P32238|
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