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Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
|Gene Name:||cholecystokinin A receptor|
|Family/Subfamily:||GPCR , Cholecystokinin|
|Synonyms:||CCKAR, CCK-A receptor, CCK-AR, CCKRA, CCK-A, CCKA receptor, Cholecystokinin A receptor, Cck1r, CCK1-R, Cholecystokinin-1 receptor|
|Target Sequences:||NM_000730 NP_000721.1 P32238|
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