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Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome.
Gene Name: | coiled-coil domain containing 78 |
Synonyms: | CCDC78, C16orf25, CNM4, JFP10, LA16c-444G9.2 |
Target Sequences: | NM_001031737 NP_001026907.2 A2IDD5 |
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