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CCDC46

centrosomal protein 112kDa

CCDC46 encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants.

Gene Name: centrosomal protein 112kDa
Synonyms: CEP112, CCDC46, Centrosomal protein of 112 kDa, Centrosomal protein 112kDa, MACOCO
Target Sequences: W28100 Q8N8E3 Q8N8E3

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CCDC46 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CCDC46 Protein - Purified recombinant protein CEP112 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.4 kDa
20 µg/$1,107
CCDC46 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.4 kDa
100 µg/$494
CCDC46 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
24.4 kDa
20 µg/$150
CCDC46 Protein - 12.5% SDS-PAGE of human CEP112 stained with Coomassie Blue
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Wheat Germ Extract
GST
50.9 kDa
10 µg/$479; 25 µg/$670
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).