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Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Gene Name: | Coiled-coil Domain Containing 109B |
Synonyms: | CCDC109B |
Target Sequences: | NM_017918 NP_060388.2 Q9NWR8 |
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