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CBX2

chromobox homolog 2

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.

Gene Name: chromobox homolog 2
Synonyms: CBX2, Chromobox homolog 2, Chromobox protein homolog 2, M33, SRXY5, CDCA6, Modifier 3, Pc class homolog
Target Sequences: NM_005189 NP_116036.1 Q14781

Publications (1)

1
Polycomb chromobox Cbx2 enhances antiviral innate immunity by promoting Jmjd3-mediated demethylation of H3K27 at the Ifnb promoter. Sun D, Cao X, Wang C. Protein & cell. 2019 April;10:285-294. [Full Text Article] [PubMed:30357595] [PMC:PMC6418077] Related Antibodies: LS-C81651.

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Products
Antibodies (42)
Primary (42)
CBX2 (42)
Human (42)
Mouse (16)
Bat (6)
Bovine (6)
Chimpanzee (6)
Gibbon (6)
Guinea pig (3)
Pig (3)
Rabbit (3)
IHC (7)
IHC-P (1)
WB (39)
Flo (1)
ChIP-Seq (1)
ELISA (26)
IF (1)
IP (2)
Peptide-ELISA (1)
rabbit (32)
mouse (9)
rabbit-new zealand white (1)
Product Group
IHCPlus (1)
IgG (25)
IgG1 (3)
IgG2a,k (6)
monoclonal mc (9)
polyclonal pc (33)
4C11B10 (1)
4D10B2 (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (18)
aa137-166 (7)
aa47-75 (7)
C-Terminus (4)
aa107-156 (4)
N-Terminal (1)
aa2-70 (1)
aa410-460 (1)
aa482-532 (1)
aa66-166 (1)
No (41)
Yes (1)
CBX2 Antibody - Heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CBX2 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
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CBX2 Rabbit anti-Human Polyclonal (aa482-532) Antibody
Human
ChIP-Seq, IP
Unconjugated
10 µg/$295; 100 µl/$514
CBX2 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CBX2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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CBX2 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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CBX2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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CBX2 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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CBX2 Mouse anti-Human Monoclonal (aa66-166) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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CBX2 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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CBX2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
CBX2 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
CBX2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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CBX2 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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CBX2 Mouse anti-Human Monoclonal (4C11B10) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
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CBX2 Rabbit anti-Human Polyclonal (N-Terminal) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CBX2 Mouse anti-Human Monoclonal (4D10B2) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
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CBX2 Rabbit-New Zealand White anti-Human Polyclonal (aa410-460) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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CBX2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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CBX2 Rabbit anti-Human Polyclonal (aa47-75) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CBX2 Rabbit anti-Human Polyclonal (aa47-75) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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CBX2 Rabbit anti-Human Polyclonal (aa137-166) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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CBX2 Rabbit anti-Human Polyclonal (aa137-166) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CBX2 Rabbit anti-Human Polyclonal (aa137-166) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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CBX2 Rabbit anti-Human Polyclonal (aa137-166) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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CBX2 Rabbit anti-Human Polyclonal (aa137-166) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
CBX2 Antibody - Western blot analysis of CBX2 using 293 whole cells lysates
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CBX2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 42 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).